moral responsibility – Kreiman Lab

March 14-18, 2019. Second International Conference on Neuroscience and Free Will. Chapmann University

Fried I, Mukamel R, Kreiman G. (2011). Internally Generated Preactivation of Single Neurons in Human Medial Frontal Cortex Predicts Volition. Neuron, 69: 548-562 | PDF

Calendar

	December 2021
Mon	Tue	Wed	Thu	Fri	Sat	Sun
		1	2	3 Theory lunch: Why (a… Theory lunch: Why (and how) is there sexual dimorphism? December 3, 2021 5:30 pm - 6:30 pm Theory Zoom will be held on 12/3 from 12:30-2PM with Josie Clowney and to help recreate the atmosphere of Theory Lunch, the Zoom will be open at 12PM. Feel free to bring your lunch, a snack and/or drink. The talk will officially begin at 12:30PM. Topic: Theory Zoom with Josie Clowney 12/3 Time: Dec 3, 2021 12:30 PM Eastern Time (US and Canada) Join Zoom meeting https://harvard.zoom.us/j/92115685838?pwd=VWsweW5OT2xtR0tKUkVvd3dJWFVEUT09 Password: theory Join by telephone (use any number to dial in) +1 312 626 6799 +1 929 436 2866 +1 301 715 8592 +1 346 248 7799 +1 669 900 6833 +1 253 215 8782 International numbers available: https://harvard.zoom.us/u/acADLRTX2n One tap mobile: +13126266799,,92115685838# US (Chicago) Join by SIP conference room system Meeting ID: 921 1568 5838 92115685838@zoomcrc.com ----------------------------------------------------------------------------------------------------------------- Why (and how) is there sexual dimorphism? Josie Clowney Department of Molecular, Celluar and Developmental Biology University of Michigan, Ann Arbor Abstract Sexual reproduction is pervasive among multicellular organisms. Combining gametes increases genetic diversity and thus species resilience by mixing alleles. In most organisms, distinct morphs – sexes – produce a large gamete (the egg) or a small gamete (the sperm). Egg and sperm are able to come together via the evolution of physical systems of mating; because the gametes are different, the different sexes that make them have different anatomies and perform distinct mating behaviors to unite them. The sexual morphs of a species develop via distinct transcriptional regulation of a common genome. I will focus on the logical principles by which concise gene regulatory systems that determine sex result in remarkably complex sexual dimorphisms in the brain. In insects, the presence of a Y chromosome in males sparks a cascade of sex-specific splicing events. This sex differentiation system uses only five genes. Two of these, doublesex and fruitless, are ultimately produced in distinct male and female versions that sex the body (doublesex) and the brain (fruitless). fruitless plays the remarkable role of exerting sex differences in the anatomy, connectivity, or physiology of dozens of disparate groups of neurons. Many or all of these neurons control sex-typical behaviors including mating, aggression, and egg-laying. I will discuss our on-going work on neuronal transcriptional regulation by fruitless and consider models by which just one factor can generate both female-specific and male-specific neurons, neural circuits, and behaviors. See more details Theory club: Emergen… Theory club: Emergent dynamics in high throughput neural data December 3, 2021 6:30 pm - 7:30 pm We are very pleased to announce that our next speaker will be Ilya Nemenman, whose talk is entitled "Emergent dynamics in high throughput neural data" (abstract below). As a reminder, the talk will take place at 12:30pm CT/1:30pm ET/10:30am PT on Friday, December 3rd. You can join the talk via Zoom using the link or meeting ID provided below. Note that the meeting link and ID are different than for the previous meeting. If you weren't able to attend last time, you can find recording of previous seminars our Youtube channel. See you then! Ilya Nemenman, Professor of Physics and Biology at Emory University Title: Emergent dynamics in high throughput neural data Abstract: Modeling in biology has firmly established itself in cases where it’s been possible to reduce a system to a relatively small number of constitutive parts (think of population dynamics models with a few species, or biophysical neural models with a handful molecular species involved). In contrast, modern experiments often measure activity of thousands of parts of a studied system, such as activities of hundreds of neurons, or frequency of hundreds of pathogenic genomes. Building computational models at this level of detail has proven difficult (and maybe not useful), and we lack intuition about how to interpret results of our experiments. Put another way: When should we be surprised by what we see in high throughput recordings? I will show that simple models can explain seemingly surprising results of high throughput experiments in fields as diverse as neuroscience and immunology (my primary focus here will be on neuroscience), and I will argue that success of these models signals emergence of simpler, collective descriptions of complex biological systems. The goal now is to identify those collective degrees of freedom, and how they interact with each other. Overall, this progress raises hopes for building predictive models of the nervous system without neurons, tissues without cells, and evolution without individuals or genes. Time: Dec 3, 2021 12:30 PM Central Time (US and Canada) Join Zoom Meeting: https://uchicago.zoom.us/j/93512790196?pwd=d1Z2MzFIYS92em8xNWM0L2F2ekE3dz09 Meeting ID: 935 1279 0196 Passcode: 895860 See more details • •	4	5
6 Neurobiology Seminar… Neurobiology Seminar: Lindsey Glickfeld December 6, 2021 5:15 pm - 6:15 pm See more details NeurIPS in person po… NeurIPS in person poster session @ Harvard December 6, 2021 8:00 pm - 11:00 pm I am writing to invite you to an in-person and local NeurIPS event! As you know, NeurIPS is online this year. To make up for the missing in-person interactions, Harvard IACS kindly agreed to host a poster session for local researchers with papers accepted to NeurIPS 2021conference and workshops. Please join us to present your work and learn about what our colleagues have been up to. The poster session will be on December 6th, 3pm-6pm in the new SEC building room LL2.223. There will be food and drinks served at LL2 atrium. We will provide poster boards (width 44 inches, height 50 inches). Please feel free to forward this e-mail to other colleagues who might be interested in attending. If you will be presenting a poster, please register through this link by December 1st: https://forms.gle/q9n8mLnKMHdRgGHD9 For visits to Harvard campus, please see the latest COVID guidance here: https://www.harvard.edu/coronavirus/campus-access/for-visitors/ Best wishes and happy thanksgiving, See more details CBS Neurotechnology … CBS Neurotechnology core open house December 6, 2021 9:00 pm - 10:00 pm NWL B401 The CBS Neurotechnology Core is hosting an open house from noon to 4pm on Dec 6th 2021 in NWL B401 See more details • • •	7 Katarina, Gabriel \| … Katarina, Gabriel \| Meeting with Prof. Kreiman December 7, 2021 5:00 pm - 6:00 pm https://bit.ly/3w6NB1p Zoom link: https://bit.ly/3w6NB1p See more details CBMM Meeting: Michal… CBMM Meeting: Michale Fee December 7, 2021 9:00 pm - 10:00 pm We hope you can join us next Tuesday for the Brains, Minds and Machines Seminar Series talk by Prof. Michale Fee, (MIT BCS): CBMM Brains, Minds, and Machines Seminar Series Speaker/s: Prof. Michale Fee, Department Head & Dorflinger Professor, Dept. Brain and Cognitive Sciences; Investigator, McGovern Institute for Brain Research; MIT Date: Tuesday, December 7, 2021 Time: 4:00 pm to 5:30 pm ET Location: Singleton Auditorium (46-3002), MIT Building 46 \| Brain and Cognitive Sciences Complex, 43 Vassar Street, Cambridge MA 02139 Abstract: TBA Event website: https://cbmm.mit.edu/news-events/events/cbmm-brains-minds-and-machines-seminar-series-prof-michale-fee-mit-bcs Speaker bio.: Michale Fee joined the McGovern Institute in 2003 and is currently the Glen V. and Phyllis F. Dorflinger Professor of Neuroscience in the Department of Brain and Cognitive Sciences. He received his PhD in Applied Physics from Stanford University in 1992. Before moving to MIT, he was a principal investigator in the Biological Computation Research Department at Bell Laboratories in New Jersey. Michale Fee studies how the brain learns and generates complex sequential behaviors, focusing on the songbird as a model system. Birdsong is a complex behavior that young birds learn from their fathers and it provides an ideal system to study the neural basis of learned behavior. Because the parts of the bird’s brain that control song learning are closely related to human circuits that are disrupted in brain disorders such as Parkinson’s and Huntington’s disease, Fee hopes the lessons learned from birdsong will provide new clues to the causes and possible treatment of these conditions. --- The Fall 2021 Brains, Minds, and Machines (BMM) Seminar Series will be hosted in a hybrid format. Please see the information included below regarding attending the event either in-person or remotely via Zoom connection. Link to attend talk remotely via Zoom: Zoom link: https://mit.zoom.us/j/93976178761?pwd=TFVPV2ZTNGk0K1hxYVNUTWFJSngyUT09 See more details • •	8 Kreiman Lab Meeting … Kreiman Lab Meeting -- Kohitij Kar December 8, 2021 5:00 pm - 7:00 pm Dr Gabriel Kreiman is inviting you to a scheduled Zoom meeting. Topic: KLAB lab meeting Time: Oct 14, 2020 12:00 PM Eastern Time (US and Canada) Every week on Wed, until Nov 4, 2020, 4 occurrence(s) Oct 14, 2020 12:00 PM Oct 21, 2020 12:00 PM Oct 28, 2020 12:00 PM Nov 4, 2020 12:00 PM See more details •	9	10	11	12
13	14 Katarina, Gabriel \| … Katarina, Gabriel \| Meeting with Prof. Kreiman December 14, 2021 5:00 pm - 6:00 pm https://bit.ly/3w6NB1p Zoom link: https://bit.ly/3w6NB1p See more details •	15 Kreiman Lab Meeting … Kreiman Lab Meeting -- Damian Blasi December 15, 2021 5:00 pm - 7:00 pm Dr Gabriel Kreiman is inviting you to a scheduled Zoom meeting. Topic: KLAB lab meeting Time: Oct 14, 2020 12:00 PM Eastern Time (US and Canada) Every week on Wed, until Nov 4, 2020, 4 occurrence(s) Oct 14, 2020 12:00 PM Oct 21, 2020 12:00 PM Oct 28, 2020 12:00 PM Nov 4, 2020 12:00 PM See more details •	16	17	18	19
20	21 Katarina, Gabriel \| … Katarina, Gabriel \| Meeting with Prof. Kreiman December 21, 2021 5:00 pm - 6:00 pm https://bit.ly/3w6NB1p Zoom link: https://bit.ly/3w6NB1p See more details •	22 Kreiman Lab Meeting Kreiman Lab Meeting December 22, 2021 5:00 pm - 7:00 pm Dr Gabriel Kreiman is inviting you to a scheduled Zoom meeting. Topic: KLAB lab meeting Time: Oct 14, 2020 12:00 PM Eastern Time (US and Canada) Every week on Wed, until Nov 4, 2020, 4 occurrence(s) Oct 14, 2020 12:00 PM Oct 21, 2020 12:00 PM Oct 28, 2020 12:00 PM Nov 4, 2020 12:00 PM See more details •	23	24	25	26
27	28 Katarina, Gabriel \| … Katarina, Gabriel \| Meeting with Prof. Kreiman December 28, 2021 5:00 pm - 6:00 pm https://bit.ly/3w6NB1p Zoom link: https://bit.ly/3w6NB1p See more details •	29 Kreiman Lab Meeting Kreiman Lab Meeting December 29, 2021 5:00 pm - 7:00 pm Dr Gabriel Kreiman is inviting you to a scheduled Zoom meeting. Topic: KLAB lab meeting Time: Oct 14, 2020 12:00 PM Eastern Time (US and Canada) Every week on Wed, until Nov 4, 2020, 4 occurrence(s) Oct 14, 2020 12:00 PM Oct 21, 2020 12:00 PM Oct 28, 2020 12:00 PM Nov 4, 2020 12:00 PM See more details •	30	31

December 2021

Why (and how) is there sexual dimorphism?

Abstract